# Fractionated and Multiple Dose 225Ac-J591 for Progressive mCRPC

> **NCT04506567** · PHASE1,PHASE2 · ACTIVE_NOT_RECRUITING · sponsor: **Weill Medical College of Cornell University** · enrollment: 60 (actual)

## Conditions studied

- Prostate Cancer

## Interventions

- **DRUG:** Fractionated dose of 225Ac-J591
- **DIAGNOSTIC_TEST:** 68Ga-PSMA-HBED-CC injection
- **DRUG:** Multiple single doses of 225Ac-J591

## Key facts

- **NCT ID:** NCT04506567
- **Lead sponsor:** Weill Medical College of Cornell University
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2020-08-18
- **Primary completion:** 2025-06-01
- **Final completion:** 2026-06
- **Target enrollment:** 60 (ACTUAL)
- **Last updated:** 2026-02-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04506567

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04506567, "Fractionated and Multiple Dose 225Ac-J591 for Progressive mCRPC". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT04506567. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*