# Message-Based Psychotherapy and Digital Treatment Sequences for Depression

> **NCT04513080** · NA · COMPLETED · sponsor: **Talkspace** · enrollment: 1184 (actual)

## Conditions studied

- Study Adherence
- Depressive Disorder

## Interventions

- **BEHAVIORAL:** Video-Chat Psychotherapy (VCP)
- **BEHAVIORAL:** Message-Based Psychotherapy (MBP)
- **BEHAVIORAL:** Message-Based Psychotherapy with Monthly Video-Chat Psychotherapy
- **BEHAVIORAL:** Message-Based Psychotherapy with Weekly Video-Chat Psychotherapy
- **BEHAVIORAL:** High Monetary Incentive (HMI)
- **BEHAVIORAL:** Low Monetary and Alternative Incentive (LMAI)

## Key facts

- **NCT ID:** NCT04513080
- **Lead sponsor:** Talkspace
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-03-02
- **Primary completion:** 2024-01-14
- **Final completion:** 2024-01-14
- **Target enrollment:** 1184 (ACTUAL)
- **Last updated:** 2025-10-30

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04513080

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04513080, "Message-Based Psychotherapy and Digital Treatment Sequences for Depression". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT04513080. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*