# ICITRU : Randomized Trial of Immunonutrition With L-citrulline in Patients Hospitalized in Intensive Care for Sepsis or Septic Shock

> **NCT04513288** · NA · RECRUITING · sponsor: **Rennes University Hospital** · enrollment: 130 (estimated)

## Conditions studied

- Sepsis
- Septic Shock

## Interventions

- **DIETARY_SUPPLEMENT:** Experimental treatment L-citrulline (Protéocit®)
- **OTHER:** Placebo treatment

## Key facts

- **NCT ID:** NCT04513288
- **Lead sponsor:** Rennes University Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2022-05-20
- **Primary completion:** 2026-11-20
- **Final completion:** 2026-11-20
- **Target enrollment:** 130 (ESTIMATED)
- **Last updated:** 2024-10-08


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04513288

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04513288, "ICITRU : Randomized Trial of Immunonutrition With L-citrulline in Patients Hospitalized in Intensive Care for Sepsis or Septic Shock". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT04513288. Licensed CC0.

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