# Mechanistic Studies of Nicotinamide Riboside in Human Heart Failure

> **NCT04528004** · EARLY_PHASE1 · ACTIVE_NOT_RECRUITING · sponsor: **University of Washington** · enrollment: 32 (actual)

## Conditions studied

- Heart Failure, Systolic
- Heart Failure NYHA Class IV
- Metabolic Disturbance

## Interventions

- **DRUG:** Nicotinamide riboside
- **OTHER:** Placebo

## Key facts

- **NCT ID:** NCT04528004
- **Lead sponsor:** University of Washington
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2020-09-26
- **Primary completion:** 2024-11-30
- **Final completion:** 2025-07-31
- **Target enrollment:** 32 (ACTUAL)
- **Last updated:** 2025-03-25

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04528004

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04528004, "Mechanistic Studies of Nicotinamide Riboside in Human Heart Failure". Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/clinical/NCT04528004. Licensed CC0.

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