# Detection of A-synuclein Aggregate as Biomarker in Diagnosing Parkinson's Disease at Early Stage by Using Protein Misfolding Cyclic Amplification (PMCA)

> **NCT04536857** · — · WITHDRAWN · sponsor: **Huashan Hospital**

## Conditions studied

- Parkinson's Disease

## Interventions

- **OTHER:** Biomarker assay

## Key facts

- **NCT ID:** NCT04536857
- **Lead sponsor:** Huashan Hospital
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** WITHDRAWN
- **Start date:** 2024-10-01
- **Primary completion:** 2025-12-30
- **Final completion:** 2025-12-30
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** Our applied project did not receive funding support, so it cannot proceed, leading to the withdrawal of the study.
- **Last updated:** 2025-03-19


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04536857

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04536857, "Detection of A-synuclein Aggregate as Biomarker in Diagnosing Parkinson's Disease at Early Stage by Using Protein Misfolding Cyclic Amplification (PMCA)". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT04536857. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*