# Cardiovascular Reserve Evaluation in Survivors of Transplant, CREST Study

> **NCT04537871** · — · ACTIVE_NOT_RECRUITING · sponsor: **City of Hope Medical Center** · enrollment: 350 (actual)

## Conditions studied

- Acute Lymphoblastic Leukemia
- Acute Myeloid Leukemia
- Hematopoietic and Lymphoid Cell Neoplasm
- Hodgkin Lymphoma
- Myelodysplastic Syndrome
- Non-Hodgkin Lymphoma
- Plasma Cell Myeloma

## Interventions

- **PROCEDURE:** Bioelectric Impedance Analysis
- **PROCEDURE:** Biospecimen Collection
- **PROCEDURE:** Cardiopulmonary Exercise Testing
- **PROCEDURE:** Echocardiography
- **PROCEDURE:** Physical Performance Testing
- **PROCEDURE:** Pulmonary Function Test
- **OTHER:** Questionnaire Administration
- **PROCEDURE:** Ultrasound

## Key facts

- **NCT ID:** NCT04537871
- **Lead sponsor:** City of Hope Medical Center
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2020-11-18
- **Primary completion:** 2026-06-30
- **Final completion:** 2026-06-30
- **Target enrollment:** 350 (ACTUAL)
- **Last updated:** 2025-09-25

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04537871

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04537871, "Cardiovascular Reserve Evaluation in Survivors of Transplant, CREST Study". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT04537871. Licensed CC0.

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