# BonE and Joint Infections - Simplifying Treatment in Children Trial

> **NCT04538053** · PHASE4 · RECRUITING · sponsor: **Murdoch Childrens Research Institute** · enrollment: 285 (estimated)

## Conditions studied

- Bone Infection
- Septic Arthritis
- Bone and Joint Infection
- Osteomyelitis

## Interventions

- **DRUG:** Oral cefalexin only
- **DRUG:** IV cefazolin or IV flucloxacillin followed by oral cefalexin

## Key facts

- **NCT ID:** NCT04538053
- **Lead sponsor:** Murdoch Childrens Research Institute
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2021-06-01
- **Primary completion:** 2026-12
- **Final completion:** 2026-12
- **Target enrollment:** 285 (ESTIMATED)
- **Last updated:** 2025-11-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04538053

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04538053, "BonE and Joint Infections - Simplifying Treatment in Children Trial". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT04538053. Licensed CC0.

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