# Serial MR Imaging and MR Spectroscopic Imaging for the Characterization of Lower Grade Glioma

> **NCT04540107** · PHASE1 · RECRUITING · sponsor: **Susan Chang** · enrollment: 300 (estimated)

## Conditions studied

- Recurrent World Health Organization (WHO) Grade II Glioma
- Recurrent WHO Grade III Glioma
- WHO Grade II Glioma
- WHO Grade III Glioma

## Interventions

- **DRUG:** Hyperpolarized Carbon C 13 Pyruvate
- **PROCEDURE:** Magnetic Resonance Imaging
- **PROCEDURE:** Magnetic Resonance Spectroscopic Imaging

## Key facts

- **NCT ID:** NCT04540107
- **Lead sponsor:** Susan Chang
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2017-01-11
- **Primary completion:** 2027-01-31
- **Final completion:** 2027-01-31
- **Target enrollment:** 300 (ESTIMATED)
- **Last updated:** 2026-04-29

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04540107

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04540107, "Serial MR Imaging and MR Spectroscopic Imaging for the Characterization of Lower Grade Glioma". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT04540107. Licensed CC0.

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