# A Study Comparing Haploidentical Hematopoietic Stem Cell Transplantations (HSCTs) From Young Non-first-degree and Older First-degree Donors in Hematological Malignancies

> **NCT04547049** · PHASE3 · ACTIVE_NOT_RECRUITING · sponsor: **First Affiliated Hospital of Zhejiang University** · enrollment: 232 (estimated)

## Conditions studied

- Leukemia
- MDS

## Interventions

- **DRUG:** Cytarabine
- **DRUG:** Busulfan
- **DRUG:** Cyclophosphamide
- **DRUG:** Me-CCNU
- **DRUG:** Rabbit antithymocyte globulin
- **PROCEDURE:** Allogeneic HSCT
- **DRUG:** Cyclosporin A
- **DRUG:** Mycophenolate Mofetil
- **DRUG:** MTX

## Key facts

- **NCT ID:** NCT04547049
- **Lead sponsor:** First Affiliated Hospital of Zhejiang University
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2020-09-01
- **Primary completion:** 2026-04-01
- **Final completion:** 2026-04-01
- **Target enrollment:** 232 (ESTIMATED)
- **Last updated:** 2026-04-09


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04547049

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04547049, "A Study Comparing Haploidentical Hematopoietic Stem Cell Transplantations (HSCTs) From Young Non-first-degree and Older First-degree Donors in Hematological Malignancies". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT04547049. Licensed CC0.

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