# Biweekly Actinomycin-D Treatment or Multi-day Methotrexate Protocol in Low-risk Gestational Trophoblastic Neoplasia

> **NCT04562558** · NA · ACTIVE_NOT_RECRUITING · sponsor: **xiang yang** · enrollment: 228 (actual)

## Conditions studied

- Gestational Trophoblastic Tumor
- Gestational Trophoblastic Neoplasia
- Stage I Gestational Trophoblastic Tumor
- Stage II Gestational Trophoblastic Tumor
- Stage III Gestational Trophoblastic Tumor
- Invasive Mole
- Choriocarcinoma

## Interventions

- **DRUG:** Methotrexate
- **DRUG:** Leucovorin
- **DRUG:** Dactinomycin

## Key facts

- **NCT ID:** NCT04562558
- **Lead sponsor:** xiang yang
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2020-09-29
- **Primary completion:** 2024-11-11
- **Final completion:** 2025-12
- **Target enrollment:** 228 (ACTUAL)
- **Last updated:** 2025-08-11


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04562558

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04562558, "Biweekly Actinomycin-D Treatment or Multi-day Methotrexate Protocol in Low-risk Gestational Trophoblastic Neoplasia". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT04562558. Licensed CC0.

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