# Risk of Recurrence of de Novo Mutations: Research and Quantification of Paternal Germinal Mosaicism by the Combined Use of Genomic Tools

> **NCT04564235** · NA · COMPLETED · sponsor: **University Hospital, Rouen** · enrollment: 5 (actual)

## Conditions studied

- Developmental Disorders

## Interventions

- **GENETIC:** genome-wide analyses
- **GENETIC:** Search for de novo mutations in paternal sperm samples

## Key facts

- **NCT ID:** NCT04564235
- **Lead sponsor:** University Hospital, Rouen
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-02-24
- **Primary completion:** 2022-12-12
- **Final completion:** 2022-12-12
- **Target enrollment:** 5 (ACTUAL)
- **Last updated:** 2026-04-20


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04564235

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04564235, "Risk of Recurrence of de Novo Mutations: Research and Quantification of Paternal Germinal Mosaicism by the Combined Use of Genomic Tools". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT04564235. Licensed CC0.

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