# Effect of Anthracyclines and Cyclophosphamide on Cardiovascular Responses

> **NCT04568161** · NA · COMPLETED · sponsor: **University of Sao Paulo General Hospital** · enrollment: 15 (actual)

## Conditions studied

- Cardiotoxicity
- Cardiovascular Disease
- Neurovascular Disorder
- Endothelial Disfunction
- Breast Cancer

## Interventions

- **PROCEDURE:** Physical Characteristics
- **PROCEDURE:** Muscular Sympathetic Nervous Activity
- **DIAGNOSTIC_TEST:** Cardiac Function
- **DIAGNOSTIC_TEST:** Heart rate
- **DIAGNOSTIC_TEST:** Blood pressure
- **DIAGNOSTIC_TEST:** Blood Assessments
- **DIAGNOSTIC_TEST:** Muscle blood flow
- **DIAGNOSTIC_TEST:** Endothelium-dependent vascular function
- **DIAGNOSTIC_TEST:** Vascular intima-media thickness
- **DIAGNOSTIC_TEST:** Physical Capacity
- **DRUG:** Anthracycline & Cyclophosphamide treatment scheme

## Key facts

- **NCT ID:** NCT04568161
- **Lead sponsor:** University of Sao Paulo General Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-08-03
- **Primary completion:** 2022-09-03
- **Final completion:** 2025-03-03
- **Target enrollment:** 15 (ACTUAL)
- **Last updated:** 2025-04-03

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04568161

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04568161, "Effect of Anthracyclines and Cyclophosphamide on Cardiovascular Responses". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT04568161. Licensed CC0.

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