# Randomized, Double-Blind Evaluation of Maple Leaf Extract (Maplifa) for Photoaging

> **NCT04586816** · NA · COMPLETED · sponsor: **Integrative Skin Science and Research** · enrollment: 19 (actual)

## Conditions studied

- Photoaging
- Hyperpigmentation
- Rhytides

## Interventions

- **COMBINATION_PRODUCT:** 1% red maple leaf extract in cream base
- **COMBINATION_PRODUCT:** 5% red maple leaf extract
- **COMBINATION_PRODUCT:** vehicle

## Key facts

- **NCT ID:** NCT04586816
- **Lead sponsor:** Integrative Skin Science and Research
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-09-10
- **Primary completion:** 2020-01-15
- **Final completion:** 2020-01-15
- **Target enrollment:** 19 (ACTUAL)
- **Last updated:** 2020-10-14

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04586816

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04586816, "Randomized, Double-Blind Evaluation of Maple Leaf Extract (Maplifa) for Photoaging". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT04586816. Licensed CC0.

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