# The Aging Brain and Cognition: Contribution of Vascular Injury, Amyloid Plaque and Tau Protein to Cognitive Dysfunction After Stroke

> **NCT04588649** · PHASE2 · COMPLETED · sponsor: **Chang Gung Memorial Hospital** · enrollment: 181 (actual)

## Conditions studied

- Post-stroke Dementia
- Vascular Mild Cognitive Impairment

## Interventions

- **DRUG:** THK-5351
- **DRUG:** AV-45

## Key facts

- **NCT ID:** NCT04588649
- **Lead sponsor:** Chang Gung Memorial Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2016-01-04
- **Primary completion:** 2016-03-29
- **Final completion:** 2019-12-31
- **Target enrollment:** 181 (ACTUAL)
- **Last updated:** 2023-05-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04588649

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04588649, "The Aging Brain and Cognition: Contribution of Vascular Injury, Amyloid Plaque and Tau Protein to Cognitive Dysfunction After Stroke". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT04588649. Licensed CC0.

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