# A Double-blind, Placebo-controlled Study of Antidepressant Augmentation With Agomelatine

> **NCT04589143** · PHASE4 · COMPLETED · sponsor: **Central South University** · enrollment: 137 (actual)

## Conditions studied

- Major Depressive Disorder

## Interventions

- **DRUG:** Agomelatine
- **DRUG:** Placebos

## Key facts

- **NCT ID:** NCT04589143
- **Lead sponsor:** Central South University
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-10-01
- **Primary completion:** 2022-12-30
- **Final completion:** 2023-01-30
- **Target enrollment:** 137 (ACTUAL)
- **Last updated:** 2024-04-01


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04589143

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04589143, "A Double-blind, Placebo-controlled Study of Antidepressant Augmentation With Agomelatine". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT04589143. Licensed CC0.

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