# Translating Metabolic Responses to Mechanical Insult Into Early Interventions to Prevent PTOA

> **NCT04589611** · PHASE1,PHASE2 · COMPLETED · sponsor: **J L Marsh** · enrollment: 5 (actual)

## Conditions studied

- Osteoarthritis
- Post-traumatic Osteoarthritis

## Interventions

- **DRUG:** amobarbital/Gel-One (one dose)
- **DRUG:** Placebo (single dose)
- **DRUG:** amobarbital/Gel-One (two doses)
- **DRUG:** Placebo (two doses)

## Key facts

- **NCT ID:** NCT04589611
- **Lead sponsor:** J L Marsh
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-07-20
- **Primary completion:** 2023-12-01
- **Final completion:** 2023-12-01
- **Target enrollment:** 5 (ACTUAL)
- **Last updated:** 2024-03-26

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04589611

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04589611, "Translating Metabolic Responses to Mechanical Insult Into Early Interventions to Prevent PTOA". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT04589611. Licensed CC0.

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