# Randomized Trial Investigating Melatonin Supplementation vs Placebo on Sleep Disturbance Following Total Joint Arthroplasty

> **NCT04590742** · NA · UNKNOWN · sponsor: **Rothman Institute Orthopaedics** · enrollment: 154 (actual)

## Conditions studied

- Sleep Disturbance
- Total Joint Arthroplasty

## Interventions

- **DRUG:** melatonin 6mg
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT04590742
- **Lead sponsor:** Rothman Institute Orthopaedics
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2018-02-27
- **Primary completion:** 2021-11-30
- **Final completion:** 2021-11-30
- **Target enrollment:** 154 (ACTUAL)
- **Last updated:** 2020-10-19


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04590742

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04590742, "Randomized Trial Investigating Melatonin Supplementation vs Placebo on Sleep Disturbance Following Total Joint Arthroplasty". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT04590742. Licensed CC0.

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