# A Safety Study of KHK4951 in Healthy Volunteers and Patients With Wet Age-Related Macular Degeneration

> **NCT04594681** · PHASE1 · TERMINATED · sponsor: **Kyowa Kirin Co., Ltd.** · enrollment: 116 (actual)

## Conditions studied

- Healthy Volunteers
- Wet Age-related Macular Degeneration

## Interventions

- **DRUG:** Placebo
- **DRUG:** KHK4951

## Key facts

- **NCT ID:** NCT04594681
- **Lead sponsor:** Kyowa Kirin Co., Ltd.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2020-09-16
- **Primary completion:** 2022-08-26
- **Final completion:** 2022-08-26
- **Target enrollment:** 116 (ACTUAL)
- **Why stopped:** The Sponsor judged that the objectives of this Phase 1 study were satisfied, and the study was terminated after the completion of Cohort 3 Step 3.
- **Last updated:** 2023-05-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04594681

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04594681, "A Safety Study of KHK4951 in Healthy Volunteers and Patients With Wet Age-Related Macular Degeneration". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT04594681. Licensed CC0.

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