# Double-blind, Randomized Controlled Study to Assess the Analgesic Effect of 2 g of Magnesium Dipyrone (Metamizol) and Changes in Plasma Beta-endorphin Immunoreactivity Values in Patients Undergoing Elective Inguinal Herniorrhaphy Under Epidural Anesthesia.

> **NCT04595877** · PHASE4 · COMPLETED · sponsor: **Antonio Martín Duce** · enrollment: 60 (actual)

## Conditions studied

- Pain
- Beta-endorphin
- Dipyrone
- Hernia Surgery

## Interventions

- **DRUG:** Dipyrone administration
- **BEHAVIORAL:** Pain assessment
- **BIOLOGICAL:** beta-endorphin immunoreactivity
- **OTHER:** Placebo administration

## Key facts

- **NCT ID:** NCT04595877
- **Lead sponsor:** Antonio Martín Duce
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2006-01
- **Primary completion:** 2006-05
- **Final completion:** 2006-05
- **Target enrollment:** 60 (ACTUAL)
- **Last updated:** 2020-10-22


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04595877

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04595877, "Double-blind, Randomized Controlled Study to Assess the Analgesic Effect of 2 g of Magnesium Dipyrone (Metamizol) and Changes in Plasma Beta-endorphin Immunoreactivity Values in Patients Undergoing Elective Inguinal Herniorrhaphy Under Epidural Anesthesia.". Retrieved via AI Analytics 2026-05-31 from https://api.ai-analytics.org/clinical/NCT04595877. Licensed CC0.

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