# Influence of Probiotics on Clinical Parameters, the Oral Microbiome and the Immune System During an Orthodontic Treatment

> **NCT04598633** · NA · UNKNOWN · sponsor: **University of Erlangen-Nürnberg** · enrollment: 34 (estimated)

## Conditions studied

- Gingivitis
- Orthodontic Appliance Complication

## Interventions

- **DIETARY_SUPPLEMENT:** Lactobacillus reuteri Prodentis®-lozenges (DSM 17938, ATCC PTA 5289)
- **DIETARY_SUPPLEMENT:** Placebo-lozenges (BioGaia)

## Key facts

- **NCT ID:** NCT04598633
- **Lead sponsor:** University of Erlangen-Nürnberg
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2020-11-24
- **Primary completion:** 2022-12-01
- **Final completion:** 2022-12-01
- **Target enrollment:** 34 (ESTIMATED)
- **Last updated:** 2022-05-18

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04598633

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04598633, "Influence of Probiotics on Clinical Parameters, the Oral Microbiome and the Immune System During an Orthodontic Treatment". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT04598633. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*