Venetoclax With Obinutuzumab and Magrolimab (VENOM) in Relapsed and Refractory Indolent B-cell Malignancies

NCT04599634 · clinicaltrials.gov ↗

PHASE1

Phase

COMPLETED

Status

11

Enrollment

NIH

Sponsor class

Conditions

Follicular Lymphoma
Marginal Zone Lymphoma
Mantle Cell Lymphoma
Chronic Lymphocytic Lymphoma
B-Cell Lymphoma

Interventions

DRUG: Obinutuzumab
DRUG: Venetoclax
DRUG: Magrolimab
DRUG: Acetaminophen
DRUG: Diphenhydramine
DRUG: Prednisone/prednisolone
DRUG: Methylprednisolone
DIAGNOSTIC_TEST: CT Scan chest/abdomen/pelvis
DIAGNOSTIC_TEST: MRI
DIAGNOSTIC_TEST: 18-FDG-PET
PROCEDURE: Bone Marrow Biopsy
PROCEDURE: Bone Marrow Aspiration

Sponsor

National Cancer Institute (NCI)