# PASSIvation of Vulnerable Plaque With AZD5718 in AcuTe Coronary syndromE

> **NCT04601467** · PHASE2 · TERMINATED · sponsor: **National University Heart Centre, Singapore** · enrollment: 243 (actual)

## Conditions studied

- Acute Coronary Syndrome

## Interventions

- **DRUG:** AZD5718
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT04601467
- **Lead sponsor:** National University Heart Centre, Singapore
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2021-07-12
- **Primary completion:** 2024-05-27
- **Final completion:** 2024-08-14
- **Target enrollment:** 243 (ACTUAL)
- **Why stopped:** The study was terminated early on 14th September 2023 by the main funding company because of financial futility. We were able to enroll 243 of the initial planned 360 participants and randomised 209 participants of the intial planned 286.
- **Last updated:** 2025-04-27

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04601467

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04601467, "PASSIvation of Vulnerable Plaque With AZD5718 in AcuTe Coronary syndromE". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT04601467. Licensed CC0.

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