# Nicotine Replacement Therapy, Counseling, Varenicline, and Bupropion for Smoking Cessation, the PISCES I Trial

> **NCT04604509** · PHASE4 · RECRUITING · sponsor: **M.D. Anderson Cancer Center** · enrollment: 2010 (estimated)

## Conditions studied

- Cigarette Smoking-Related Carcinoma

## Interventions

- **DRUG:** Bupropion Hydrochloride Controlled-release
- **DRUG:** Nicotine Replacement
- **OTHER:** Questionnaire Administration
- **OTHER:** Tobacco Cessation Counseling
- **DRUG:** Varenicline

## Key facts

- **NCT ID:** NCT04604509
- **Lead sponsor:** M.D. Anderson Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2020-08-04
- **Primary completion:** 2028-12-31
- **Final completion:** 2028-12-31
- **Target enrollment:** 2010 (ESTIMATED)
- **Last updated:** 2026-05-04

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04604509

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04604509, "Nicotine Replacement Therapy, Counseling, Varenicline, and Bupropion for Smoking Cessation, the PISCES I Trial". Retrieved via AI Analytics 2026-06-05 from https://api.ai-analytics.org/clinical/NCT04604509. Licensed CC0.

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