# Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of GSK3915393 in Healthy Participants and to Evaluate the Interaction Between GSK3915393 and Grapefruit Juice and Itraconazole

> **NCT04604795** · PHASE1 · COMPLETED · sponsor: **GlaxoSmithKline** · enrollment: 65 (actual)

## Conditions studied

- Celiac Disease
- Coeliac Disease

## Interventions

- **DRUG:** GSK3915393 Capsules
- **DRUG:** GSK3915393 Solution for Infusion
- **DRUG:** Placebo capsules
- **DRUG:** Itraconazole
- **OTHER:** Water
- **OTHER:** Grape fruit juice

## Key facts

- **NCT ID:** NCT04604795
- **Lead sponsor:** GlaxoSmithKline
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-11-04
- **Primary completion:** 2021-06-29
- **Final completion:** 2021-06-29
- **Target enrollment:** 65 (ACTUAL)
- **Last updated:** 2023-05-09


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04604795

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04604795, "Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of GSK3915393 in Healthy Participants and to Evaluate the Interaction Between GSK3915393 and Grapefruit Juice and Itraconazole". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT04604795. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*