Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Primary CNS Lymphoma

NCT04609046 · clinicaltrials.gov ↗

PHASE1

Phase

RECRUITING

Status

47

Enrollment

NIH

Sponsor class

Conditions

Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System

Interventions

PROCEDURE: Bone Marrow Aspiration and Biopsy
PROCEDURE: Computed Tomography
PROCEDURE: Echocardiography Test
DRUG: Lenalidomide
PROCEDURE: Lumbar Puncture
PROCEDURE: Magnetic Resonance Imaging
DRUG: Methotrexate
BIOLOGICAL: Nivolumab
PROCEDURE: Positron Emission Tomography
BIOLOGICAL: Rituximab
PROCEDURE: Ultrasound Imaging

Sponsor

National Cancer Institute (NCI)