# Effect of Chewing a Calcium Supplement Before Fluoride Rinse on Salivary Fluoride

> **NCT04620252** · EARLY_PHASE1 · COMPLETED · sponsor: **University of Michigan** · enrollment: 18 (actual)

## Conditions studied

- Dental Caries

## Interventions

- **DRUG:** Inactive supplement
- **DRUG:** Tricalcium phosphate supplement
- **DRUG:** Calcium carbonate supplement
- **DRUG:** Calcium citrate supplement
- **DRUG:** Inactive supplement and fluoride mouthwash
- **DRUG:** Calcium carbonate supplement and fluoride mouthwash
- **DRUG:** Calcium citrate supplement and fluoride mouthwash

## Key facts

- **NCT ID:** NCT04620252
- **Lead sponsor:** University of Michigan
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-02-01
- **Primary completion:** 2022-03-31
- **Final completion:** 2022-03-31
- **Target enrollment:** 18 (ACTUAL)
- **Last updated:** 2022-05-09


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04620252

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04620252, "Effect of Chewing a Calcium Supplement Before Fluoride Rinse on Salivary Fluoride". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT04620252. Licensed CC0.

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