# Sodium Bicarbonate Ringer's Solution Versus Normal Saline for Early Fluid Resuscitation in Patients With Sepsis

> **NCT04621981** · NA · UNKNOWN · sponsor: **Xiangya Hospital of Central South University** · enrollment: 450 (estimated)

## Conditions studied

- Sepsis, Septic Shock

## Interventions

- **DRUG:** Sodium Bicarbonate Ringer's Solution
- **DRUG:** Normal Saline

## Key facts

- **NCT ID:** NCT04621981
- **Lead sponsor:** Xiangya Hospital of Central South University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2021-03-11
- **Primary completion:** 2022-09-30
- **Final completion:** 2022-12-30
- **Target enrollment:** 450 (ESTIMATED)
- **Last updated:** 2022-04-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04621981

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04621981, "Sodium Bicarbonate Ringer's Solution Versus Normal Saline for Early Fluid Resuscitation in Patients With Sepsis". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT04621981. Licensed CC0.

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