# Effects of Ezetimibe Combination Therapy for Patients With Atherosclerotic Cardiovascular Disease; Randomized Comparison of LDL-cholesterol Targeting <70 Versus <55mg/dL; Ez-PAVE Trial

> **NCT04626973** · NA · COMPLETED · sponsor: **Yonsei University** · enrollment: 3048 (actual)

## Conditions studied

- Atherosclerotic Cardiovascular Disease

## Interventions

- **DRUG:** Ezetimibe/Statin Combination therarpy (ezetimibe plus rosuvastatin)
- **DRUG:** Statin monotherapy (rosuvastatin or atorvastatin)
- **DRUG:** Ezetimibe/Statin Combination therarpy (ezetimibe plus rosuvastatin)
- **DRUG:** Statin monotherapy (rosuvastatin or atorvastatin)

## Key facts

- **NCT ID:** NCT04626973
- **Lead sponsor:** Yonsei University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-01-15
- **Primary completion:** 2025-09-24
- **Final completion:** 2025-09-24
- **Target enrollment:** 3048 (ACTUAL)
- **Last updated:** 2025-11-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04626973

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04626973, "Effects of Ezetimibe Combination Therapy for Patients With Atherosclerotic Cardiovascular Disease; Randomized Comparison of LDL-cholesterol Targeting <70 Versus <55mg/dL; Ez-PAVE Trial". Retrieved via AI Analytics 2026-07-18 from https://api.ai-analytics.org/clinical/NCT04626973. Licensed CC0.

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