# Long-term Effects of Transcutaneous Vagal Nerve Stimulation on Postural Orthostatic Tachycardia Syndrome (POTS)

> **NCT04632134** · NA · UNKNOWN · sponsor: **Istituto Clinico Humanitas** · enrollment: 23 (estimated)

## Conditions studied

- Orthostatic Intolerance
- Postural Tachycardia Syndrome
- Syncope, Postural
- Physical Disability
- Autonomic Dysfunction

## Interventions

- **DEVICE:** Transcutaneous vagal nerve stimulation (tVNS)
- **OTHER:** Placebo
- **DEVICE:** Home daily transcutaneous vagal nerve stimulation

## Key facts

- **NCT ID:** NCT04632134
- **Lead sponsor:** Istituto Clinico Humanitas
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2019-11-10
- **Primary completion:** 2022-06-30
- **Final completion:** 2022-12-30
- **Target enrollment:** 23 (ESTIMATED)
- **Last updated:** 2022-06-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04632134

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04632134, "Long-term Effects of Transcutaneous Vagal Nerve Stimulation on Postural Orthostatic Tachycardia Syndrome (POTS)". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT04632134. Licensed CC0.

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