# Changes in Oral Health in Tobacco Cigarettes Smokers After Switching to Combustion-Free Nicotine Delivery Systems

> **NCT04649645** · NA · COMPLETED · sponsor: **Eclat Srl.** · enrollment: 460 (actual)

## Conditions studied

- Gingivitis
- Periodontal Diseases

## Interventions

- **OTHER:** TOBACCO CIGARETTES
- **OTHER:** COMBUSTION-FREE NICOTINE DELIVERY SYSTEMS (C-F NDS)
- **OTHER:** NOT SMOKING

## Key facts

- **NCT ID:** NCT04649645
- **Lead sponsor:** Eclat Srl.
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-10-18
- **Primary completion:** 2024-12-19
- **Final completion:** 2024-12-19
- **Target enrollment:** 460 (ACTUAL)
- **Last updated:** 2025-09-08

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04649645

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04649645, "Changes in Oral Health in Tobacco Cigarettes Smokers After Switching to Combustion-Free Nicotine Delivery Systems". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT04649645. Licensed CC0.

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