# Randomized Control Trial to Compare Standard Monitoring and Plethysmographic Variability Index-Guided Fluid Therapy In 64 Severe Traumatic Brain Injury Patients, Aged 18 to 60 Years Old Undergoing Emergency Craniotomies

> **NCT04664699** · NA · COMPLETED · sponsor: **Universiti Sains Malaysia** · enrollment: 64 (actual)

## Conditions studied

- Severe Traumatic Brain Injury

## Interventions

- **DEVICE:** Plethymographic Variability Index
- **DEVICE:** Standard Monitoring

## Key facts

- **NCT ID:** NCT04664699
- **Lead sponsor:** Universiti Sains Malaysia
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-05-29
- **Primary completion:** 2020-10-30
- **Final completion:** 2020-10-30
- **Target enrollment:** 64 (ACTUAL)
- **Last updated:** 2020-12-11


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04664699

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04664699, "Randomized Control Trial to Compare Standard Monitoring and Plethysmographic Variability Index-Guided Fluid Therapy In 64 Severe Traumatic Brain Injury Patients, Aged 18 to 60 Years Old Undergoing Emergency Craniotomies". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT04664699. Licensed CC0.

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