# Safety and Efficacy of Nyxol With Pilocarpine Eye Drops in Subjects With Presbyopia

> **NCT04675151** · PHASE2 · COMPLETED · sponsor: **Ocuphire Pharma, Inc.** · enrollment: 150 (actual)

## Conditions studied

- Presbyopia

## Interventions

- **DRUG:** Phentolamine Ophthalmic Solution 0.75%
- **DRUG:** Pilocarpine
- **OTHER:** Placebo

## Key facts

- **NCT ID:** NCT04675151
- **Lead sponsor:** Ocuphire Pharma, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-02-15
- **Primary completion:** 2021-05-17
- **Final completion:** 2021-06-30
- **Target enrollment:** 150 (ACTUAL)
- **Last updated:** 2025-10-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04675151

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04675151, "Safety and Efficacy of Nyxol With Pilocarpine Eye Drops in Subjects With Presbyopia". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT04675151. Licensed CC0.

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