# Induction Therapy for Lupus Nephritis With no Added Oral Steroids: A Trial Comparing Oral Corticosteroids Plus Mycophenolate Mofetil (MMF) Versus Obinutuzumab and MMF

> **NCT04702256** · PHASE3 · RECRUITING · sponsor: **Assistance Publique - Hôpitaux de Paris** · enrollment: 196 (estimated)

## Conditions studied

- Lupus Nephritis
- Systemic Lupus Erythematosus (SLE)

## Interventions

- **DRUG:** Obinutuzumab administration
- **DRUG:** Administration of Methylprednisolone + Prednisone + Mycophenolate mofetil
- **DRUG:** Administration of methylprednisolone, paracetamol and dexchlorpheniramine

## Key facts

- **NCT ID:** NCT04702256
- **Lead sponsor:** Assistance Publique - Hôpitaux de Paris
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2021-12-09
- **Primary completion:** 2031-12
- **Final completion:** 2031-12
- **Target enrollment:** 196 (ESTIMATED)
- **Last updated:** 2025-11-24

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04702256

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04702256, "Induction Therapy for Lupus Nephritis With no Added Oral Steroids: A Trial Comparing Oral Corticosteroids Plus Mycophenolate Mofetil (MMF) Versus Obinutuzumab and MMF". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT04702256. Licensed CC0.

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