# University of Pittsburgh Brain Health Initiative

> **NCT04708613** · — · RECRUITING · sponsor: **David Okonkwo, MD, PhD** · enrollment: 300 (estimated)

## Conditions studied

- Traumatic Brain Injury

## Interventions

- **DIAGNOSTIC_TEST:** Cognitive/Neuropsychological Testing
- **DIAGNOSTIC_TEST:** Vestibular/Ocular-Motor Testing
- **DIAGNOSTIC_TEST:** Sleep Evaluation
- **DIAGNOSTIC_TEST:** MRI, High-Resolution
- **DIAGNOSTIC_TEST:** Health & Physical Exam
- **DIAGNOSTIC_TEST:** Physical Function
- **DIAGNOSTIC_TEST:** Blood Testing and Biomarker Analysis
- **DIAGNOSTIC_TEST:** Applanation Tonometry
- **DIAGNOSTIC_TEST:** PET brain imaging
- **DRUG:** [C-11]6-OH-BTA-1
- **DRUG:** [F-18]AV-1451

## Key facts

- **NCT ID:** NCT04708613
- **Lead sponsor:** David Okonkwo, MD, PhD
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2019-11-18
- **Primary completion:** 2026-12
- **Final completion:** 2026-12
- **Target enrollment:** 300 (ESTIMATED)
- **Last updated:** 2025-06-13

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04708613

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04708613, "University of Pittsburgh Brain Health Initiative". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT04708613. Licensed CC0.

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