# Clinical Stabilization of Hypercapnia: NIPPV v HVNI

> **NCT04709562** · NA · COMPLETED · sponsor: **Vapotherm, Inc.** · enrollment: 68 (actual)

## Conditions studied

- Hypercapnic Respiratory Failure
- Chronic Obstructive Pulmonary Disease
- Dyspnea
- Hypercapnic Acidosis

## Interventions

- **DEVICE:** High Velocity Nasal Insufflation (HVNI)
- **DEVICE:** Noninvasive Positive Pressure Ventilation (NIPPV)

## Key facts

- **NCT ID:** NCT04709562
- **Lead sponsor:** Vapotherm, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-11-11
- **Primary completion:** 2023-05-26
- **Final completion:** 2023-06-22
- **Target enrollment:** 68 (ACTUAL)
- **Last updated:** 2024-08-09

## Collaborators

- [object Object]
- [object Object]
- [object Object]
- [object Object]
- [object Object]
- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04709562

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04709562, "Clinical Stabilization of Hypercapnia: NIPPV v HVNI". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT04709562. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*