# Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia

> **NCT04712812** · — · RECRUITING · sponsor: **Boston Children's Hospital** · enrollment: 700 (estimated)

## Conditions studied

- Hereditary Spastic Paraplegia
- SPG47
- SPG50
- SPG51
- SPG52
- AP4-related Hereditary Spastic Paraplegia
- Early Onset Hereditary Spastic Paraplegia
- SPG4
- SPG3A
- SPG15
- SPG11

## Interventions

_None listed._

## Key facts

- **NCT ID:** NCT04712812
- **Lead sponsor:** Boston Children's Hospital
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2020-04-27
- **Primary completion:** 2030-12-31
- **Final completion:** 2030-12-31
- **Target enrollment:** 700 (ESTIMATED)
- **Last updated:** 2026-03-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04712812

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04712812, "Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT04712812. Licensed CC0.

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