# Comparison of High Flow Nasal Cannula (HFNC), Face-mask Non-Invasive Ventilation (NIV) & Helmet NIV in COVID-19 ARDS Patients

> **NCT04715243** · NA · TERMINATED · sponsor: **Sultan Qaboos University** · enrollment: 161 (actual)

## Conditions studied

- Acute Respiratory Distress Syndrome Caused by COVID-19

## Interventions

- **DEVICE:** High flow nasal cannula (HFNC)
- **DEVICE:** Helmet NIV
- **DEVICE:** Face-mask NIV

## Key facts

- **NCT ID:** NCT04715243
- **Lead sponsor:** Sultan Qaboos University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2021-02-02
- **Primary completion:** 2021-08-09
- **Final completion:** 2021-11-11
- **Target enrollment:** 161 (ACTUAL)
- **Why stopped:** 1. Futility
2. Lack of recruitment in the centers due to lack of cases meeting the study criterial despite period of extension.
- **Last updated:** 2022-01-12


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04715243

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04715243, "Comparison of High Flow Nasal Cannula (HFNC), Face-mask Non-Invasive Ventilation (NIV) & Helmet NIV in COVID-19 ARDS Patients". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT04715243. Licensed CC0.

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