# Dronabinol in Total Knee Arthroplasty (TKA)

> **NCT04734080** · PHASE4 · COMPLETED · sponsor: **Hospital for Special Surgery, New York** · enrollment: 114 (actual)

## Conditions studied

- Total Knee Arthroplasty
- Opioid Use

## Interventions

- **DRUG:** Dronabinol 5mg Cap
- **OTHER:** Placebo oral tablet

## Key facts

- **NCT ID:** NCT04734080
- **Lead sponsor:** Hospital for Special Surgery, New York
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-03-09
- **Primary completion:** 2023-10-06
- **Final completion:** 2024-04-01
- **Target enrollment:** 114 (ACTUAL)
- **Last updated:** 2026-03-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04734080

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04734080, "Dronabinol in Total Knee Arthroplasty (TKA)". Retrieved via AI Analytics 2026-05-31 from https://api.ai-analytics.org/clinical/NCT04734080. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*