# International Multicenter Patent foRamen OVale & strokE (IMPROVE) Registry

> **NCT04738071** · — · UNKNOWN · sponsor: **London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's** · enrollment: 3730 (actual)

## Conditions studied

- Stroke
- Patent Foramen Ovale
- Atrial Fibrillation
- Atrial Flutter

## Interventions

- **DEVICE:** PFO closure

## Key facts

- **NCT ID:** NCT04738071
- **Lead sponsor:** London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** UNKNOWN
- **Start date:** 2019-11-13
- **Primary completion:** 2022-11-13
- **Final completion:** 2025-11-13
- **Target enrollment:** 3730 (ACTUAL)
- **Last updated:** 2024-03-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04738071

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04738071, "International Multicenter Patent foRamen OVale & strokE (IMPROVE) Registry". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT04738071. Licensed CC0.

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