# Neoantigen Vaccine Therapy Against H3.3-K27M Diffuse Intrinsic Pontine Glioma

> **NCT04749641** · PHASE1 · COMPLETED · sponsor: **Yang Zhang** · enrollment: 16 (actual)

## Conditions studied

- Diffuse Intrinsic Pontine Glioma

## Interventions

- **BIOLOGICAL:** Histone H3.3-K27M Neoantigen Vaccine Therapy

## Key facts

- **NCT ID:** NCT04749641
- **Lead sponsor:** Yang Zhang
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-03-08
- **Primary completion:** 2024-10-14
- **Final completion:** 2024-10-14
- **Target enrollment:** 16 (ACTUAL)
- **Last updated:** 2025-06-06

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04749641

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04749641, "Neoantigen Vaccine Therapy Against H3.3-K27M Diffuse Intrinsic Pontine Glioma". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT04749641. Licensed CC0.

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