# Cholinergic Mechanisms of Attention in Aging

> **NCT04756232** · EARLY_PHASE1 · COMPLETED · sponsor: **Vanderbilt University Medical Center** · enrollment: 19 (actual)

## Conditions studied

- Subjective Cognitive Decline

## Interventions

- **DRUG:** Mecamylamine Challenge
- **OTHER:** Placebo Comparator Challenge

## Key facts

- **NCT ID:** NCT04756232
- **Lead sponsor:** Vanderbilt University Medical Center
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-04-21
- **Primary completion:** 2025-04-30
- **Final completion:** 2025-05-01
- **Target enrollment:** 19 (ACTUAL)
- **Last updated:** 2025-09-05


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04756232

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04756232, "Cholinergic Mechanisms of Attention in Aging". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT04756232. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*