# Metformin as Maintenance Therapy in Patients With Bone Sarcoma and High Risk of Relapse

> **NCT04758000** · PHASE2 · RECRUITING · sponsor: **Istituto Ortopedico Rizzoli** · enrollment: 67 (estimated)

## Conditions studied

- Osteosarcoma
- Ewing Sarcoma

## Interventions

- **DRUG:** Metformin Hydrochloride

## Key facts

- **NCT ID:** NCT04758000
- **Lead sponsor:** Istituto Ortopedico Rizzoli
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2021-03-01
- **Primary completion:** 2027-07
- **Final completion:** 2027-07
- **Target enrollment:** 67 (ESTIMATED)
- **Last updated:** 2023-08-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04758000

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04758000, "Metformin as Maintenance Therapy in Patients With Bone Sarcoma and High Risk of Relapse". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT04758000. Licensed CC0.

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