# Fecal Microbiota Transplantation to Improve Efficacy of Immune Checkpoint Inhibitors in Renal Cell Carcinoma

> **NCT04758507** · PHASE1,PHASE2 · COMPLETED · sponsor: **Fondazione Policlinico Universitario Agostino Gemelli IRCCS** · enrollment: 50 (actual)

## Conditions studied

- Renal Cell Carcinoma

## Interventions

- **BIOLOGICAL:** donor FMT
- **OTHER:** Placebo FMT

## Key facts

- **NCT ID:** NCT04758507
- **Lead sponsor:** Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-02-18
- **Primary completion:** 2024-12-16
- **Final completion:** 2025-07-28
- **Target enrollment:** 50 (ACTUAL)
- **Last updated:** 2025-09-08


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04758507

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04758507, "Fecal Microbiota Transplantation to Improve Efficacy of Immune Checkpoint Inhibitors in Renal Cell Carcinoma". Retrieved via AI Analytics 2026-06-05 from https://api.ai-analytics.org/clinical/NCT04758507. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*