Treatment of Restless Legs Symptoms With Pramipexole to Improve the Outcomes of Protracted Opioid Withdrawal in OUD

Stopped An interim analysis indicated that we would need to enroll more subjects than our initial enrollment target, in order to demonstrate a significant treatment effect. Due to these results, we have decided to terminate this protocol.

Conditions

• Sleep Disorder
• Restless Legs Syndrome
• Opioid-use Disorder
• Opioid Withdrawal

Interventions

• DRUG: Pramipexole
• DRUG: Placebo

Sponsor

Massachusetts General Hospital