# Study to Assess Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of Palovarotene Ophthalmic Solution in Healthy Adult Subjects

> **NCT04762355** · PHASE1 · COMPLETED · sponsor: **Clementia Pharmaceuticals Inc.** · enrollment: 48 (actual)

## Conditions studied

- Dry Eye Disease

## Interventions

- **DRUG:** Palovarotene
- **DRUG:** Vehicle

## Key facts

- **NCT ID:** NCT04762355
- **Lead sponsor:** Clementia Pharmaceuticals Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-08-30
- **Primary completion:** 2019-01-03
- **Final completion:** 2019-01-03
- **Target enrollment:** 48 (ACTUAL)
- **Last updated:** 2021-02-21

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04762355

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04762355, "Study to Assess Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of Palovarotene Ophthalmic Solution in Healthy Adult Subjects". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT04762355. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*