# The Effect of Induced Hyperammonaemia on Sleep and Melanopsin-mediated Pupillary Light Response in Patients With Liver Cirrhosis

> **NCT04771104** · NA · COMPLETED · sponsor: **Rigshospitalet, Denmark** · enrollment: 9 (actual)

## Conditions studied

- Hepatic Encephalopathy
- Liver Cirrhosis
- Sleep Disturbance

## Interventions

- **DIETARY_SUPPLEMENT:** Amino Acid Challenge (AAC)

## Key facts

- **NCT ID:** NCT04771104
- **Lead sponsor:** Rigshospitalet, Denmark
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-01-01
- **Primary completion:** 2018-01-09
- **Final completion:** 2018-01-22
- **Target enrollment:** 9 (ACTUAL)
- **Last updated:** 2021-03-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04771104

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04771104, "The Effect of Induced Hyperammonaemia on Sleep and Melanopsin-mediated Pupillary Light Response in Patients With Liver Cirrhosis". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT04771104. Licensed CC0.

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