# A Prospective Study for the Treatment of Children With Newly Diagnosed LCH Using a Cytarabine Contained Protocol

> **NCT04773366** · PHASE3 · RECRUITING · sponsor: **Shanghai Children's Medical Center** · enrollment: 200 (estimated)

## Conditions studied

- Langerhans Cell Histiocytosis

## Interventions

- **DRUG:** Prednisone+Cytarabine+vincristine
- **DRUG:** Prednisone+Cytarabine+vincristine+Mercaptopurine
- **DRUG:** Prednisone+Cytarabine+vincristine+Mercaptopurine
- **DRUG:** Prednisone+Cytarabine+vincristine
- **DRUG:** Prednisone+vincristine+Mercaptopurine
- **DRUG:** Prednisone+vincristine
- **DRUG:** Prednisone+vincristine
- **OTHER:** Local therapy

## Key facts

- **NCT ID:** NCT04773366
- **Lead sponsor:** Shanghai Children's Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2018-07-01
- **Primary completion:** 2023-06-30
- **Final completion:** 2026-06-30
- **Target enrollment:** 200 (ESTIMATED)
- **Last updated:** 2022-07-26


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04773366

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04773366, "A Prospective Study for the Treatment of Children With Newly Diagnosed LCH Using a Cytarabine Contained Protocol". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT04773366. Licensed CC0.

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