# Transplantation of Clustered Regularly Interspaced Short Palindromic Repeats Modified Hematopoietic Progenitor Stem Cells (CRISPR_SCD001) in Patients With Severe Sickle Cell Disease

> **NCT04774536** · PHASE1,PHASE2 · RECRUITING · sponsor: **Mark Walters, MD** · enrollment: 9 (estimated)

## Conditions studied

- Sickle Cell Disease

## Interventions

- **DRUG:** CRISPR_SCD001

## Key facts

- **NCT ID:** NCT04774536
- **Lead sponsor:** Mark Walters, MD
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-08-22
- **Primary completion:** 2030-03-01
- **Final completion:** 2030-03-01
- **Target enrollment:** 9 (ESTIMATED)
- **Last updated:** 2026-04-16

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04774536

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04774536, "Transplantation of Clustered Regularly Interspaced Short Palindromic Repeats Modified Hematopoietic Progenitor Stem Cells (CRISPR_SCD001) in Patients With Severe Sickle Cell Disease". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT04774536. Licensed CC0.

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