Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain Metastases

NCT04789668 · clinicaltrials.gov ↗

PHASE1,PHASE2

Phase

TERMINATED

Status

8

Enrollment

OTHER

Sponsor class

Stopped Insufficient accrual

Conditions

Anatomic Stage IV Breast Cancer AJCC v8
Clinical Stage IV Cutaneous Melanoma AJCC v8
Hematopoietic and Lymphoid Cell Neoplasm
Hormone Receptor Positive Breast Adenocarcinoma
Metastatic Lung Non-Small Cell Carcinoma
Metastatic Malignant Neoplasm in the Brain
Metastatic Malignant Solid Neoplasm
Metastatic Melanoma
Metastatic Triple-Negative Breast Carcinoma
Pathologic Stage IV Cutaneous Melanoma AJCC v8
Prognostic Stage IV Breast Cancer AJCC v8
Stage IV Lung Cancer AJCC v8
Stage IVA Lung Cancer AJCC v8
Stage IVB Lung Cancer AJCC v8

Interventions

DRUG: Bintrafusp Alfa
DRUG: Pimasertib
OTHER: Quality-of-Life Assessment

Sponsor

M.D. Anderson Cancer Center