# Melatonin Use After Primary Total Joint Arthroplasty

> **NCT04795336** · PHASE1 · COMPLETED · sponsor: **NYU Langone Health** · enrollment: 294 (actual)

## Conditions studied

- Osteo Arthritis Knee

## Interventions

- **DRUG:** Melatonin 5 mg
- **OTHER:** Placebo

## Key facts

- **NCT ID:** NCT04795336
- **Lead sponsor:** NYU Langone Health
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-07-12
- **Primary completion:** 2024-04-01
- **Final completion:** 2024-04-18
- **Target enrollment:** 294 (ACTUAL)
- **Last updated:** 2025-05-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04795336

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04795336, "Melatonin Use After Primary Total Joint Arthroplasty". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT04795336. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*